Medication Overuse Headaches (MOH), also known as rebound headaches, are the third most common type of headache after tension headache and migraine. MOH should be considered when headache is present for 15 days or more per month and has developed or worsened while taking regular pain relief medications medications such as triptans, opioids, ergots, paracetamol (tylenol), aspirin, other non-steroidal anti-inflammatory drugs (NSAIDs) or combinations of these. MOH is 5 times more common in women than men.
One study1 found an association between variant genes and risk of Medication Overuse Headaches in patients after 2 months of pain medication overuse.
triptans, opioids, ergots, paracetamol, tylenol, aspirin, non-steroidal anti-inflammatory drugs / NSAIDs, rebound headache