Multiple Chemical Sensitivity

Multiple chemical sensitivity (MCS) is a chronic medical condition characterized by symptoms that affect a person's response to low-level chemical exposure. It is also known as "environmental illness", "sick building syndrome" or "idiopathic environmental intolerance". Multiple chemical sensitivity includes a wide range of symptoms such as: headache, fatigue, dizziness, nausea, congestion, itching, sneezing, sore throat, chest pain, changes in heart rhythm, breathing problems, muscle pain or stiffness, skin rash, diarrhea, bloating, gas, confusion, trouble concentrating, memory problems, and mood changes. Potential triggers include tobacco smoke, auto exhaust, perfume, insecticide, new carpet and chlorine.

Results from a case-control study1 indicated that there was an increased risk of high chemical sensitivity associated with the SOD2 gene. SOD2 encodes a member of the Superoxide dismutase family. These enzymes play a pivotal role in protecting cells from free radicals and oxidative damage.2 Overexpression of SOD2 is associated with increased levels of Hydrogen peroxide, a major contributor to oxidative stress3.

Related to:
MCS, SOD2, oxidative stress, environmental illness, sick building syndrome, idiopathic environmental intolerance