Crohn's disease causes inflammation of the digestive system. It is one of a group of diseases called inflammatory bowel disease. Crohn's can affect any area from the mouth to the anus. It often affects the lower part of the small intestine called the ileum.
Glucocorticoid drugs reduce inflammation and are commonly used to treat auto-immune conditions like Crohn's disease. A study1 of single-nucleotide polymorphisms (SNPs) of the glucocorticoid receptor and FKBP5 genes was able to identify subgroups of Crohn's disease patients with higher chances to benefit from glucocorticoid treatment